Paternal age and birth defects: how strong is the association?

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Paternal age and birth defects: how strong is the association?

BACKGROUND Although the association between maternal age and the risks of birth defects has been well studied, the evidence from population data linking paternal age with birth defects was limited and inconsistent. METHODS We conducted a population-based retrospective cohort study of 5,213,248 subjects from the 1999-2000 birth registration data of the USA. Multiple logistic regressions were u...

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Is paternal age associated with an increased risk of low birthweight, preterm delivery, and multiple birth?

OBJECTIVE To determine if paternal age elevates the risk of low birthweight (< 2500g, LBW), preterm birth (< 37 weeks gestation), and multiple gestation among mothers whose age does not predict an elevated risk. DESIGN/METHODS Population data on birth outcome, maternal age and paternal age was obtained from Alberta Health and Wellness for all births 1990-1996. RESULTS Among women aged 25 to...

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Paternal age and adverse birth outcomes: teenager or 40+, who is at risk?

BACKGROUND Most previous studies on the effect of paternal age have focused on the association of advanced paternal age with congenital anomalies. The objective of this study was to determine whether paternal age is associated with the risk of adverse birth outcomes, independent of maternal confounders. METHODS We carried out a retrospective cohort study of 2 614 966 live singletons born to m...

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Paternal Occupational Exposure to 2,3,7,8-Tetrachlorodibenzo-p-dioxin and Birth Outcomes of Offspring: Birth Weight, Preterm Delivery, and Birth Defects

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ژورنال

عنوان ژورنال: Human Reproduction

سال: 2006

ISSN: 1460-2350,0268-1161

DOI: 10.1093/humrep/del453